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Opposing effects of multivalent ions on flexibility of DNA and RNA

Increasing concentration of counterions (salt) is known to reduce the bending persistence length of DNA. Here we use atomistic molecular dynamics simulations to predict that multivalent counterions have the opposite effect on double-stranded RNA, increasing its bending rigidity by at least 30%. This...

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Detalhes bibliográficos
Publicado no:Phys Rev Lett
Main Authors: Drozdetski, Aleksander V., Tolokh, Igor S., Pollack, Lois, Baker, Nathan, Onufriev, Alexey V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493319/
https://ncbi.nlm.nih.gov/pubmed/27447528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevLett.117.028101
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