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Structural basis of MeCP2 distribution on non-CpG methylated and hydroxymethylated DNA
The Rett syndrome-associated methyl-CpG binding protein 2 (MeCP2) selectively binds methylated DNA to regulate transcription during the development of mature neurons. Like other members of the methyl-CpG binding domain (MBD) family, MeCP2 functions through the recognition of symmetrical 5-methylcyto...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5492995/ https://ncbi.nlm.nih.gov/pubmed/28450074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.04.009 |
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