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Elevated cerebrospinal fluid tumor necrosis factor is associated with acute and long-term neurocognitive impairment in cerebral malaria

Systemic tumor necrosis factor-α (TNF-α) may contribute to the pathogenesis of cerebral malaria (CM) by promoting endothelial activation and parasite sequestration. However less is known about the role of central nervous system (CNS) TNF-α in CM. We assessed plasma (n=249) and cerebrospinal fluid (C...

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Detalhes bibliográficos
Publicado no:Parasite Immunol
Main Authors: Shabani, Estela, Ouma, Benson J., Idro, Richard, Bangirana, Paul, Opoka, Robert O., Park, Gregory S., Conroy, Andrea L., John, Chandy C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492989/
https://ncbi.nlm.nih.gov/pubmed/28453871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pim.12438
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