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Modeling T(H)2 responses and airway inflammation to understand fundamental mechanisms regulating the pathogenesis of asthma

In this review, we highlight experiments conducted in our laboratories that have elucidated functional roles for CD4(+) T-helper type-2 lymphocytes (T(H)2 cells), their associated cytokines and eosinophils in the regulation of hallmark features of allergic asthma. Notably, we consider the complexity...

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Dettagli Bibliografici
Pubblicato in:Immunol Rev
Autori principali: Foster, Paul S., Maltby, Steven, Rosenberg, Helene F., Tay, Hock L., Hogan, Simon P., Collison, Adam M., Yang, Ming, Kaiko, Gerard E., Hansbro, Philip M., Kumar, Rakesh K., Mattes, Joerg
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492958/
https://ncbi.nlm.nih.gov/pubmed/28658543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12549
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