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Expression of an additional cathelicidin antimicrobial peptide protects against bacterial skin infection

Cathelicidin antimicrobial peptides are effectors of innate immune defense in mammals. Humans and mice have only one cathelicidin gene, whereas domesticated mammals such as the pig, cow, and horse have multiple cathelicidin genes. We hypothesized that the evolution of multiple cathelicidin genes pro...

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書誌詳細
主要な著者: Lee, Phillip H. A., Ohtake, Takaaki, Zaiou, Mohamed, Murakami, Masamoto, Rudisill, Jennifer A., Lin, Kenneth H., Gallo, Richard L.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC549293/
https://ncbi.nlm.nih.gov/pubmed/15728389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500268102
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