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A NIR-Emitting Lysosome-Targeting Probe with Large Stokes Shift via Coupling Cyanine and Excited-State Intramolecular Proton Transfer

An NIR-emitting probe (λ(em)~700 nm) with a large Stokes shift (Δλ≈234 nm) is synthesized by using excited-state intramolecular proton transfer (ESIPT). The phenolic proton, which controls ESIPT, acts as a switch to give strong fluorescence at pH≈5. The probe can selectively show lysosome organelles...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Dahal, Dipendra, McDonald, Lucas, Bi, Xiaoman, Abeywickrama, Chathura, Gombedaz, Farai, Konopka, Michael, Paruchuri, Sailaja, Pang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492890/
https://ncbi.nlm.nih.gov/pubmed/28294245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc00700k
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