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Evaluation of Ceftobiprole in a Rabbit Model of Aortic Valve Endocarditis Due to Methicillin-Resistant and Vancomycin-Intermediate Staphylococcus aureus
Ceftobiprole is a novel broad-spectrum cephalosporin that binds with high affinity to PBP 2a, the methicillin-resistance determinant of staphylococci, and is active against methicillin- and vancomycin-resistant Staphylococcus aureus. Ceftobiprole was compared to vancomycin in a rabbit model of methi...
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| Format: | Artigo |
| Jezik: | Inglês |
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American Society for Microbiology
2005
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549268/ https://ncbi.nlm.nih.gov/pubmed/15728879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.3.884-888.2005 |
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