Human CD6 Down-Modulation following T-Cell Activation Compromises Lymphocyte Survival and Proliferative Responses

Available evidence indicates that the CD6 lymphocyte surface receptor is involved in T-cell developmental and activation processes, by facilitating cell-to-cell adhesive contacts with antigen-presenting cells and likely modulating T-cell receptor (TCR) signaling. Here, we show that in vitro activati...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Carrasco, Esther, Escoda-Ferran, Cristina, Climent, Núria, Miró-Julià, Cristina, Simões, Inês T., Martínez-Florensa, Mario, Sarukhan, Adelaida, Carreras, Esther, Lozano, Francisco
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492662/
https://ncbi.nlm.nih.gov/pubmed/28713387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00769
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