Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis

[Image: see text] Hyaluronan is a biologically active polymer, which can be formulated into nanoparticles. In our study, we aimed to probe atherosclerosis-associated inflammation by using hyaluronan nanoparticles and to determine whether they can ameliorate atherosclerosis. Hyaluronan nanoparticles...

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Veröffentlicht in:ACS Nano
Hauptverfasser: Beldman, Thijs J., Senders, Max L., Alaarg, Amr, Pérez-Medina, Carlos, Tang, Jun, Zhao, Yiming, Fay, Francois, Deichmöller, Jacqueline, Born, Benjamin, Desclos, Emilie, van der Wel, Nicole N., Hoebe, Ron A., Kohen, Fortune, Kartvelishvily, Elena, Neeman, Michal, Reiner, Thomas, Calcagno, Claudia, Fayad, Zahi A., de Winther, Menno P. J., Lutgens, Esther, Mulder, Willem J. M., Kluza, Ewelina
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2017
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492212/
https://ncbi.nlm.nih.gov/pubmed/28463501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.7b01385
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