Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis

[Image: see text] Hyaluronan is a biologically active polymer, which can be formulated into nanoparticles. In our study, we aimed to probe atherosclerosis-associated inflammation by using hyaluronan nanoparticles and to determine whether they can ameliorate atherosclerosis. Hyaluronan nanoparticles...

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Vydáno v:ACS Nano
Hlavní autoři: Beldman, Thijs J., Senders, Max L., Alaarg, Amr, Pérez-Medina, Carlos, Tang, Jun, Zhao, Yiming, Fay, Francois, Deichmöller, Jacqueline, Born, Benjamin, Desclos, Emilie, van der Wel, Nicole N., Hoebe, Ron A., Kohen, Fortune, Kartvelishvily, Elena, Neeman, Michal, Reiner, Thomas, Calcagno, Claudia, Fayad, Zahi A., de Winther, Menno P. J., Lutgens, Esther, Mulder, Willem J. M., Kluza, Ewelina
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2017
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492212/
https://ncbi.nlm.nih.gov/pubmed/28463501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.7b01385
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