Impairment of Granzyme B-Producing Regulatory B Cells Correlates with Exacerbated Rheumatoid Arthritis

Hyperactivated B cells have been demonstrated the contribution to the development of rheumatoid arthritis (RA). While the recognition of the negative regulatory function of B cells further promoted our understanding of their pathogenic role in RA. Recently, a new population of granzyme B (GrB)-produ...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Xu, Liling, Liu, Xu, Liu, Hongjiang, Zhu, Lei, Zhu, Huaqun, Zhang, Jian, Ren, Limin, Wang, Pingzhang, Hu, Fanlei, Su, Yin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491972/
https://ncbi.nlm.nih.gov/pubmed/28713386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00768
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