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Diagnosing the miR-141 prostate cancer biomarker using nucleic acid-functionalized CdSe/ZnS QDs and telomerase

The microRNA, miR-141, is a promising biomarker for prostate cancer. We implement here a two-step sensing platform for the sensitive detection of miR-141. The first step involves the use of semiconductor CdSe/ZnS quantum dots (QDs) modified by FRET quencher-functionalized nucleic acids, that include...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Jou, Amily Fang-ju, Lu, Chun-Hua, Ou, Yen-Chuan, Wang, Shian-Shiang, Hsu, Shih-Lan, Willner, Itamar, Ho, Ja-an Annie
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491954/
https://ncbi.nlm.nih.gov/pubmed/28706633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc02104e
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