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Phosphate increase during fatigue affects crossbridge kinetics in intact mouse muscle at physiological temperature

KEY POINTS: Actomyosin ATP hydrolysis occurring during muscle contraction releases inorganic phosphate [P(i)] in the myoplasm. High [P(i)] reduces force and affects force kinetics in skinned muscle fibres at low temperature. These effects decrease at high temperature, raising the question of their i...

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Bibliographic Details
Published in:J Physiol
Main Authors: Nocella, M., Cecchi, G., Colombini, B.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491871/
https://ncbi.nlm.nih.gov/pubmed/28332714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273672
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