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Structure-function analysis of human sucrase-isomaltase identifies key residues required for catalytic activity

Sucrase-isomaltase (SI) is an intestinal membrane-associated α-glucosidase that breaks down di- and oligosaccharides to absorbable monosaccharides. SI has two homologous functional subunits (sucrase and isomaltase) that both belong to the glycoside hydrolase family 31 (GH31) and differ in substrate...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Gericke, Birthe, Schecker, Natalie, Amiri, Mahdi, Naim, Hassan Y.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491789/
https://ncbi.nlm.nih.gov/pubmed/28522605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.791939
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