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Structure-function analysis of human sucrase-isomaltase identifies key residues required for catalytic activity

Sucrase-isomaltase (SI) is an intestinal membrane-associated α-glucosidase that breaks down di- and oligosaccharides to absorbable monosaccharides. SI has two homologous functional subunits (sucrase and isomaltase) that both belong to the glycoside hydrolase family 31 (GH31) and differ in substrate...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gericke, Birthe, Schecker, Natalie, Amiri, Mahdi, Naim, Hassan Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491789/
https://ncbi.nlm.nih.gov/pubmed/28522605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.791939
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