Myostatin inhibits osteoblastic differentiation by suppressing osteocyte-derived exosomal microRNA-218: A novel mechanism in muscle-bone communication

Muscle and bone are closely associated in both anatomy and function, but the mechanisms that coordinate their synergistic action remain poorly defined. Myostatin, a myokine secreted by muscles, has been shown to inhibit muscle growth, and the disruption of the myostatin gene has been reported to cau...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Qin, Yiwen, Peng, Yuanzhen, Zhao, Wei, Pan, Jianping, Ksiezak-Reding, Hanna, Cardozo, Christopher, Wu, Yingjie, Divieti Pajevic, Paola, Bonewald, Lynda F., Bauman, William A., Qin, Weiping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491785/
https://ncbi.nlm.nih.gov/pubmed/28465350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.770941
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