A retinoid X receptor (RXR)-selective retinoid reveals that RXR-α is potentially a therapeutic target in breast cancer cell lines, and that it potentiates antiproliferative and apoptotic responses to peroxisome proliferator-activated receptor ligands

INTRODUCTION: Certain lipids have been shown to be ligands for a subgroup of the nuclear hormone receptor superfamily known as the peroxisome proliferator-activated receptors (PPARs). Ligands for these transcription factors have been used in experimental cancer therapies. PPARs heterodimerize and bi...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Breast Cancer Res
Päätekijät: Crowe, David L, Chandraratna, Roshantha AS
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2004
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549174/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15318936/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/bcr913
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