Desensitized D2 autoreceptors are resistant to trafficking

Dendritic release of dopamine activates dopamine D2 autoreceptors, which are inhibitory G protein-coupled receptors (GPCRs), to decrease the excitability of dopamine neurons. This study used tagged D2 receptors to identify the localization and distribution of these receptors in living midbrain dopam...

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Publicado en:Sci Rep
Autores principales: Robinson, Brooks G., Bunzow, James R., Grimm, Jonathan B., Lavis, Luke D., Dudman, Joshua T., Brown, Jennifer, Neve, Kim A., Williams, John T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491503/
https://ncbi.nlm.nih.gov/pubmed/28663556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04728-z
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