Inhibition of Reticulon-1A–Mediated Endoplasmic Reticulum Stress in Early AKI Attenuates Renal Fibrosis Development

Several animal studies have shown an important role for endoplasmic reticulum (ER) stress in AKI, whereas human studies are lacking. We recently reported that Reticulon-1A (RTN1A) is a key mediator of ER stress and kidney cell injury. Here, we investigated whether modulation of RTN1A expression duri...

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Bibliographic Details
Published in:J Am Soc Nephrol
Main Authors: Fan, Ying, Xiao, Wenzhen, Lee, Kyung, Salem, Fadi, Wen, Jiejun, He, Li, Zhang, Jing, Fei, Yang, Cheng, Dongsheng, Bao, Hongda, Liu, Yumei, Lin, Fujun, Jiang, Gengru, Guo, Zhiyong, Wang, Niansong, He, John Cijiang
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2017
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491287/
https://ncbi.nlm.nih.gov/pubmed/28137829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016091001
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