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The NLRP3 Inflammasome Has a Critical Role in Peritoneal Dialysis-Related Peritonitis
Bacterial peritonitis remains the main cause of technique failure in peritoneal dialysis (PD). During peritonitis, the peritoneal membrane undergoes structural and functional alterations that are mediated by IL-1β. The NLRP3 inflammasome is a caspase-1–activating multiprotein complex that links sens...
Gespeichert in:
Veröffentlicht in: | J Am Soc Nephrol |
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Hauptverfasser: | , , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
American Society of Nephrology
2017
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5491280/ https://ncbi.nlm.nih.gov/pubmed/28193826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016070729 |
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