Long chain fatty acids alter the interactive binding of ligands to the two principal drug binding sites of human serum albumin

A wide variety of drugs bind to human serum albumin (HSA) at its two principal sites, namely site I and site II. A number of reports indicate that drug binding to these two binding sites are not completely independent, and that interactions between ligands of these two discrete sites can play a role...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Yamasaki, Keishi, Hyodo, Saya, Taguchi, Kazuaki, Nishi, Koji, Yamaotsu, Noriyuki, Hirono, Shuichi, Chuang, Victor Tuan Giam, Seo, Hakaru, Maruyama, Toru, Otagiri, Masaki
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2017
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491222/
https://ncbi.nlm.nih.gov/pubmed/28662200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180404
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