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Targeting neuronal gap junctions in mouse retina offers neuroprotection in glaucoma

The progressive death of retinal ganglion cells and resulting visual deficits are hallmarks of glaucoma, but the underlying mechanisms remain unclear. In many neurodegenerative diseases, cell death induced by primary insult is followed by a wave of secondary loss. Gap junctions (GJs), intercellular...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Akopian, Abram, Kumar, Sandeep, Ramakrishnan, Hariharasubramanian, Roy, Kaushambi, Viswanathan, Suresh, Bloomfield, Stewart A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490768/
https://ncbi.nlm.nih.gov/pubmed/28604388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI91948
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