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Altered homeostatic regulation of innate and adaptive immunity in lower gastrointestinal tract GVHD pathogenesis

Lower gastrointestinal (GI) tract graft-versus-host disease (GVHD) is the predominant cause of morbidity and mortality from GVHD after allogeneic stem cell transplantation. Recent data indicate that lower GI tract GVHD is a complicated process mediated by donor/host antigenic disparities. This proce...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Ferrara, James L.M., Smith, Christopher M., Sheets, Julia, Reddy, Pavan, Serody, Jonathan S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490758/
https://ncbi.nlm.nih.gov/pubmed/28581444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90592
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