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Arcuate neuropeptide Y inhibits sympathetic nerve activity via multiple neuropathways

Obesity increases sympathetic nerve activity (SNA) via activation of proopiomelanocortin neurons in the arcuate nucleus (ArcN), and this action requires simultaneous withdrawal of tonic neuropeptide Y (NPY) sympathoinhibition. However, the sites and neurocircuitry by which NPY decreases SNA are uncl...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Shi, Zhigang, Madden, Christopher J., Brooks, Virginia L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490747/
https://ncbi.nlm.nih.gov/pubmed/28628036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92008
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