SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency

Transcriptional latency of HIV is a last barrier to viral eradication. Chromatin-remodeling complexes and post-translational histone modifications likely play key roles in HIV-1 reactivation but the underlying mechanisms are incompletely understood. We performed a RNAi-based screen of human lysine m...

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Dettagli Bibliografici
Pubblicato in:Cell Host Microbe
Autori principali: Boehm, Daniela, Jeng, Mark, Camus, Gregory, Gramatica, Andrea, Schwarzer, Roland, Johnson, Jeffrey R., Hull, Philip A., Montano, Mauricio, Sakane, Naoki, Pagans, Sara, Godin, Robert, Deeks, Steven G., Krogan, Nevan J., Greene, Warner C., Ott, Melanie
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490666/
https://ncbi.nlm.nih.gov/pubmed/28494238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.04.011
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