Influence of protein fold stability on immunogenicity and its implications for vaccine design

Introduction: In modern vaccinology and immunotherapy, recombinant proteins more and more replace whole organisms to induce protective or curative immune responses. Structural stability of proteins is of crucial importance for efficient presentation of antigenic peptides on MHC, which plays a decisi...

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Bibliografiske detaljer
Udgivet i:Expert Rev Vaccines
Main Authors: Scheiblhofer, Sandra, Laimer, Josef, Machado, Yoan, Weiss, Richard, Thalhamer, Josef
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490637/
https://ncbi.nlm.nih.gov/pubmed/28290225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14760584.2017.1306441
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