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Large inter-individual variation of the pharmacodynamic effect of anticoagulant drugs on thrombin generation
Anticoagulation by a standard dosage of an inhibitor of thrombin generation presupposes predictable pharmacokinetics and pharmacodynamics of the anticoagulant. We determined the inter-individual variation of the effect on thrombin generation of a fixed concentration of direct and antithrombin-mediat...
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| Publicado no: | Haematologica |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ferrata Storti Foundation
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5490471/ https://ncbi.nlm.nih.gov/pubmed/23100275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.073601 |
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