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Abnormalities in alternative splicing of angiogenesis-related genes and their role in HIV-related cancers

Alternative splicing of mRNA leads to an increase in proteome biodiversity by allowing the generation of multiple mRNAs, coding for multiple protein isoforms of various structural and functional properties from a single primary pre-mRNA transcript. The protein isoforms produced are tightly regulated...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:HIV AIDS (Auckl)
Hauptverfasser: Mthembu, Nonkululeko N, Mbita, Zukile, Hull, Rodney, Dlamini, Zodwa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490432/
https://ncbi.nlm.nih.gov/pubmed/28694706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/HIV.S124911
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