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Improved de novo structure prediction in CASP11 by incorporating coevolution information into Rosetta

We describe CASP11 de novo blind structure predictions made using the Rosetta structure prediction methodology with both automatic and human assisted protocols. Model accuracy was generally improved using coevolution derived residue–residue contact information as restraints during Rosetta conformati...

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Detalhes bibliográficos
Publicado no:Proteins
Main Authors: Ovchinnikov, Sergey, Kim, David E., Wang, Ray Yu-Ruei, Liu, Yuan, DiMaio, Frank, Baker, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490371/
https://ncbi.nlm.nih.gov/pubmed/26677056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24974
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