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Caffeine inhibits hypothalamic A(1)R to excite oxytocin neuron and ameliorate dietary obesity in mice
Caffeine, an antagonist of the adenosine receptor A(1)R, is used as a dietary supplement to reduce body weight, although the underlying mechanism is unclear. Here, we report that adenosine level in the cerebrospinal fluid, and hypothalamic expression of A(1)R, are increased in the diet-induced obesi...
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| Foilsithe in: | Nat Commun |
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| Main Authors: | , , , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Nature Publishing Group
2017
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5490268/ https://ncbi.nlm.nih.gov/pubmed/28654087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15904 |
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