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Low-volume resuscitation with normal saline is associated with microvascular endothelial dysfunction after hemorrhage in rats, compared to colloids and balanced crystalloids

BACKGROUND: Restoration of endothelial glycocalyx (EG) barrier may be an essential therapeutic target for successful resuscitation. The aim of this study was to compare in vivo the effects of resuscitation with normal saline (NS) to lactated Ringer’s solution (LR), 5% albumin and fresh frozen plasma...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Torres, Luciana N., Chung, Kevin K., Salgado, Christi L., Dubick, Michael A., Torres Filho, Ivo P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490091/
https://ncbi.nlm.nih.gov/pubmed/28659186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-017-1745-7
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