Verapamil suppresses cardiac alternans and ventricular arrhythmias in acute myocardial ischemia via ryanodine receptor inhibition

T-wave alternans (TWA) is a potent arrhythmia substrate under the conditions of acute myocardial ischemia. Abnormal intracellular calcium cycling contributes to the genesis of cardiac alternans. Ryanodine receptor (RyR) is a pivotal Ca(2+) cycling protein central to Ca(2+) signaling in the heart. He...

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Dades bibliogràfiques
Publicat a:Am J Transl Res
Autors principals: Deng, Yu-Lei, Zhao, Jun-Yan, Yao, Ji-Hua, Tang, Qiang, Zhang, Le, Zhou, Hong-Lian, Zhang, Cun-Tai, Lv, Jia-Gao, Quan, Xiao-Qing
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489875/
https://ncbi.nlm.nih.gov/pubmed/28670363
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