Transcriptional coactivator PGC-1α regulates chondrogenesis via association with Sox9

Chondrogenesis is a multistep pathway in which multipotential mesenchymal stem cells (MSC) differentiate into chondrocytes. The transcription factor Sox9 (SRY-related high mobility group-Box gene 9) regulates chondrocyte differentiation and cartilage-specific expression of genes, such as Col2a1 (col...

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Autori principali: Kawakami, Yasuhiko, Tsuda, Masanao, Takahashi, Shigeru, Taniguchi, Noboru, Esteban, Concepción Rodríguez, Zemmyo, Michihisa, Furumatsu, Takayuki, Lotz, Martin, Belmonte, Juan Carlos Izpisúa, Asahara, Hiroshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC548985/
https://ncbi.nlm.nih.gov/pubmed/15699338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407510102
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