Accelerated versus standard epirubicin followed by cyclophosphamide, methotrexate, and fluorouracil or capecitabine as adjuvant therapy for breast cancer in the randomised UK TACT2 trial (CRUK/05/19): a multicentre, phase 3, open-label, randomised, controlled trial

BACKGROUND: Adjuvant chemotherapy for early breast cancer has improved outcomes but causes toxicity. The UK TACT2 trial used a 2×2 factorial design to test two hypotheses: whether use of accelerated epirubicin would improve time to tumour recurrence (TTR); and whether use of oral capecitabine instea...

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Detalhes bibliográficos
Publicado no:Lancet Oncol
Main Authors: Cameron, David, Morden, James P, Canney, Peter, Velikova, Galina, Coleman, Robert, Bartlett, John, Agrawal, Rajiv, Banerji, Jane, Bertelli, Gianfilippo, Bloomfield, David, Brunt, A Murray, Earl, Helena, Ellis, Paul, Gaunt, Claire, Gillman, Alexa, Hearfield, Nicholas, Laing, Robert, Murray, Nicholas, Couper, Niki, Stein, Robert C, Verrill, Mark, Wardley, Andrew, Barrett-Lee, Peter, Bliss, Judith M
Formato: Artigo
Idioma:Inglês
Publicado em: Lancet Pub. Group 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489700/
https://ncbi.nlm.nih.gov/pubmed/28600210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(17)30404-7
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