MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis

Current treatments for rheumatoid arthritis (RA) do not reverse underlying aberrant immune function. A genetic predisposition to RA, such as HLA-DR4 positivity, indicates that dendritic cells (DC) are of crucial importance to pathogenesis by activating auto-reactive lymphocytes. Here we show that mi...

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Publicado no:Nat Commun
Main Authors: Kurowska-Stolarska, Mariola, Alivernini, Stefano, Melchor, Emma Garcia, Elmesmari, Aziza, Tolusso, Barbara, Tange, Clare, Petricca, Luca, Gilchrist, Derek S., Di Sante, Gabriele, Keijzer, Chantal, Stewart, Lynn, Di Mario, Clara, Morrison, Vicky, Brewer, James M., Porter, Duncan, Milling, Simon, Baxter, Ronald D., McCarey, David, Gremese, Elisa, Lemke, Greg, Ferraccioli, Gianfranco, McSharry, Charles, McInnes, Iain B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489689/
https://ncbi.nlm.nih.gov/pubmed/28639625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15877
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