Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression

Long noncoding RNAs (lncRNAs) have been implicated in hypoxia/HIF-1-associated cancer progression through largely unknown mechanisms. Here we identify MIR31HG as a hypoxia-inducible lncRNA and therefore we name it LncHIFCAR (long noncoding HIF-1α co-activating RNA); we describe its oncogenic role as...

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Publicado en:Nat Commun
Main Authors: Shih, Jing-Wen, Chiang, Wei-Fan, Wu, Alexander T. H., Wu, Ming-Heng, Wang, Ling-Yu, Yu, Yen-Ling, Hung, Yu-Wen, Wang, Wen-Chang, Chu, Cheng-Ying, Hung, Chiu-Lien, Changou, Chun A., Yen, Yun, Kung, Hsing-Jien
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489688/
https://ncbi.nlm.nih.gov/pubmed/28639619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15874
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