TET1-mediated DNA hypomethylation regulates the expression of MUC4 in lung cancer

Lung cancer remains a disease of high mortality, despite advanced diagnostic techniques. Mucins (MUC) play crucial roles in carcinogenesis and tumor invasion in lung neoplasms. Our immunohistochemistry (IHC) studies have shown that high MUC4 expression correlates with a poor outcome. We have also sh...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Genes Cancer
Autori principali: Yokoyama, Seiya, Higashi, Michiyo, Tsutsumida, Hideaki, Wakimoto, Jouji, Hamada, Tomofumi, Wiest, Edwin, Matsuo, Kei, Kitazono, Ikumi, Goto, Yuko, Guo, Xin, Hamada, Taiji, Yamada, Sohsuke, Hiraki, Tsubasa, Yonezawa, Suguru, Batra, Surinder K., Hollingsworth, Michael A., Tanimoto, Akihide
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489649/
https://ncbi.nlm.nih.gov/pubmed/28680536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.139
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