Protein Phosphorylation and Mineral Binding Affect the Secondary Structure of the Leucine-Rich Amelogenin Peptide

Previously, we have shown that serine-16 phosphorylation in native full-length porcine amelogenin (P173) and the Leucine-Rich Amelogenin Peptide (LRAP(+P)), an alternative amelogenin splice product, affects protein assembly and mineralization in vitro. Notably, P173 and LRAP(+P) stabilize amorphous...

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Publicado en:Front Physiol
Autores principales: Yamazaki, Hajime, Beniash, Elia, Yamakoshi, Yasuo, Simmer, James P., Margolis, Henry C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489624/
https://ncbi.nlm.nih.gov/pubmed/28706493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00450
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