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The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment

Post-translational modifications of conserved N-terminal tail residues in histones regulate many aspects of chromosome activity. Thr 3 of histone H3 is highly conserved, but the significance of its phosphorylation is unclear, and the identity of the corresponding kinase unknown. Immunostaining with...

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Autors principals: Dai, Jun, Sultan, Sammy, Taylor, Stephen S., Higgins, Jonathan M.G.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC548948/
https://ncbi.nlm.nih.gov/pubmed/15681610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1267105
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