Topography of calcium phosphate ceramics regulates primary cilia length and TGF receptor recruitment associated with osteogenesis

The surface topography of synthetic biomaterials is known to play a role in material-driven osteogenesis. Recent studies show that TGFβ signalling also initiates osteogenic differentiation. TGFβ signalling requires the recruitment of TGFβ receptors (TGFβR) to the primary cilia. In this study, we hyp...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Zhang, Jingwei, Dalbay, Melis T., Luo, Xiaoman, Vrij, Erik, Barbieri, Davide, Moroni, Lorenzo, de Bruijn, Joost D., van Blitterswijk, Clemens A., Chapple, J. Paul, Knight, Martin M., Yuan, Huipin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Full Length Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489417/
https://ncbi.nlm.nih.gov/pubmed/28456657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2017.04.004
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