Human osteoblasts in vitro secrete tissue inhibitor of metalloproteinases and gelatinase but not interstitial collagenase as major cellular products.

Human osteoblast cultures (hOB) were examined for the production of interstitial collagenase, tissue inhibitor of metalloproteinases (TIMP), and gelatinolytic enzymes. Cells were isolated by bacterial collagenase digestion of trabecular bone (vertebra, rib, tibia, and femur) from 11 subjects (neonat...

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Bibliografski detalji

Izdano u:	J Clin Invest
Glavni autori:	Rifas, L, Halstead, L R, Peck, W A, Avioli, L V, Welgus, H G
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Clinical Investigation 1989
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548933/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2547836/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114216
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