TWIST1-WDR5-Hottip regulates Hoxa9 chromatin to facilitate prostate cancer metastasis

TWIST1 is a transcription factor critical for development which can promote prostate cancer metastasis. During embryonic development, TWIST1 and HOXA9 are co-expressed in mouse prostate and then silenced post-natally. Here we report that TWIST1 and HOXA9 co-expression are re-activated in mouse and h...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Malek, Reem, Gajula, Rajendra P., Williams, Russell D., Nghiem, Belinda, Simons, Brian W., Nugent, Katriana, Wang, Hailun, Taparra, Kekoa, Lemtiri-Chlieh, Ghali, Yoon, Arum R., True, Lawrence, An, Steven S., DeWeese, Theodore L., Ross, Ashley E., Schaeffer, Edward M., Pienta, Kenneth J., Hurley, Paula J., Morrissey, Colm, Tran, Phuoc T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489316/
https://ncbi.nlm.nih.gov/pubmed/28484075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2797
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