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Immunogenicity and protective efficacy of recombinant Bacille Calmette-Guerin strains expressing mycobacterium antigens Ag85A, CFP10, ESAT-6, GM-CSF and IL-12p70

Objective: This study aimed to evaluate the immunogenicity and protective efficacy of recombinant bacille calmette-guerin (rBCG) strains expressing Ag85A (A), CFP10 (C), ESAT6 (E), IL-12p70 (I), and fusion protein GM-CSF (G). Method: rBCGs were established by integrating of A, C, E, I, G, AE, CE, IE...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Dai, Fu-Ying, Wang, Jun-Fang, Gong, Xue-Li, Bao, Lang
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489297/
https://ncbi.nlm.nih.gov/pubmed/28301284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2017.1279771
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