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Mycobacteria induce TPL-2 mediated IL-10 in IL-4-generated alternatively activated macrophages

IL-4 drives expansion of Th2 cells that cause generation of alternatively activated macrophages (AAMs). Filarial infections are established early in life, induce increased IL-4 production are co-endemic with tuberculosis (TB). We sought to understand, therefore, how mycobacteria are handled in the c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chatterjee, Soumya, Talaat, Kawsar R., van Seventer, Emily E., Feng, Carl G., Scott, Alan L., Jedlicka, Anne, Dziedzic, Amanda, Nutman, Thomas B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489173/
https://ncbi.nlm.nih.gov/pubmed/28658262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179701
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