Validating α-particle emission from (211)At-labeled antibodies in single cells for cancer radioimmunotherapy using CR-39 plastic nuclear track detectors

Recently, (211)At has received increasing attention as a potential radionuclide for cancer radioimmunotherapy. It is a α-particle emitter, which is extremely effective against malignant cells. We demonstrate a method to verify the efficiency of (211)At-labeled trastuzumab antibodies ((211)At-trastuz...

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Publicat a:PLoS One
Autors principals: Kodaira, Satoshi, Li, Huizi Keiko, Konishi, Teruaki, Kitamura, Hisashi, Kurano, Mieko, Hasegawa, Sumitaka
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489156/
https://ncbi.nlm.nih.gov/pubmed/28658304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178472
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