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Binding and internalization of somatostatin, insulin, and glucagon by cultured rat islet cells.

The pathways by which islet B, A, and D cells bind and internalize homologous (self) and heterologous (other) islet hormones were compared. [125I-Tyr]Somatostatin-14 (S-14), 125I-insulin, and 125I-glucagon were incubated with monolayer cultures of neonatal rat islet cells. Tissues were processed for...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Amherdt, M, Patel, Y C, Orci, L
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1989
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548898/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2569474/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114181
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