Neurog2 and Ascl1 together regulate a postmitotic derepression circuit to govern laminar fate specification in the murine neocortex

A derepression mode of cell-fate specification involving the transcriptional repressors Tbr1, Fezf2, Satb2, and Ctip2 operates in neocortical projection neurons to specify six layer identities in sequence. Less well understood is how laminar fate transitions are regulated in cortical progenitors. Th...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Dennis, Daniel J., Wilkinson, Grey, Li, Saiqun, Dixit, Rajiv, Adnani, Lata, Balakrishnan, Anjali, Han, Sisu, Kovach, Christopher, Gruenig, Nicole, Kurrasch, Deborah M., Dyck, Richard H., Schuurmans, Carol
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488939/
https://ncbi.nlm.nih.gov/pubmed/28584103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701495114
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