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Metformin ameliorates diabetic nephropathy in a rat model of low-dose streptozotocin-induced diabetes

The present study aimed to explore the renoprotective effect of metformin on diabetic nephropathy in type 2 diabetic rats. A rat model of type 2 diabetic nephropathy (T2DN) was successfully induced via a high-fat diet combined with a single low-dose of streptozotocin. Metformin was administered intr...

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Publicat a:Exp Ther Med
Autors principals: Zhang, Siwei, Xu, Huali, Yu, Xiaofeng, Wu, Yi, Sui, Dayun
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488633/
https://ncbi.nlm.nih.gov/pubmed/28672943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4475
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