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Treatment of severe hospital-acquired and ventilator-associated pneumonia: a systematic review of inclusion and judgment criteria used in randomized controlled trials

BACKGROUND: Hospital-acquired and ventilator-associated pneumonia (HAP/VAP) are often selected for randomized clinical trials (RCTs) aiming at new drug approval. Guidelines for the design of such RCTs have been repeatedly updated by regulatory agencies. We hypothesized that large variability in the...

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Bibliographische Detailangaben
Veröffentlicht in:Crit Care
Hauptverfasser: Weiss, Emmanuel, Essaied, Wafa, Adrie, Christophe, Zahar, Jean-Ralph, Timsit, Jean-François
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488424/
https://ncbi.nlm.nih.gov/pubmed/28655326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-017-1755-5
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