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Prevention of dendritic and synaptic deficits and cognitive impairment with a neurotrophic compound

BACKGROUND: The use of neurotrophic factors to treat Alzheimer’s disease (AD) is hindered by their blood–brain barrier impermeability, short half-life, and severe side effects. Peptide 021 (P021) is a neurotrophic/neurogenic tetra-peptide that was derived from the most active region of the ciliary n...

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Bibliographic Details
Published in:Alzheimers Res Ther
Main Authors: Baazaoui, Narjes, Iqbal, Khalid
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488423/
https://ncbi.nlm.nih.gov/pubmed/28655344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-017-0273-7
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