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Bacterial DNA Protects Monocytic Cells against HIV-Vpr–Induced Mitochondrial Membrane Depolarization

Monocytes and macrophages are important HIV reservoirs, as they exhibit marked resistance to apoptosis upon infection. However, the mechanism underlying resistance to apoptosis in these cells is poorly understood. Using HIV–viral protein R-52–96 aa peptide (Vpr), we show that primary monocytes and T...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Saxena, Mansi, Busca, Aurelia, Holcik, Martin, Kumar, Ashok
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488333/
https://ncbi.nlm.nih.gov/pubmed/26969755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402379
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