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AEOL 10150 Mitigates Radiation-Induced Lung Injury in the Nonhuman Primate: Morbidity and Mortality are Administration Schedule-Dependent

Pneumonitis and fibrosis are potentially lethal, delayed effects of acute radiation exposure. In this study, male rhesus macaques received whole-thorax lung irradiation (WTLI) with a target dose of 10.74 Gy prescribed to midplane at a dose rate of 0.80 ± 0.05 Gy/min using 6 MV linear accelerator-der...

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Publicat a:Radiat Res
Autors principals: MacVittie, Thomas J., Gibbs, Allison, Farese, Ann M., Barrow, Kory, Bennett, Alexander, Taylor-Howell, Cheryl, Kazi, Abdul, Prado, Karl, Parker, George, Jackson, William
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488289/
https://ncbi.nlm.nih.gov/pubmed/28208025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR4413.1
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